New reports of respiratory symptoms and prevalence of COPD at SAPALDIA 2 in formerly asymptomatic participants with and without BHR at SAPALDIA 1
| Symptoms developed between surveys | Asymptomatic at baseline | p value | |
|---|---|---|---|
| No BHR(n = 3439) | BHR(n = 492) | ||
| *COPD was defined as FEV1/FVC <0.70 and no physician’s diagnosis of asthma. | |||
| Physician-diagnosed asthma (%) | 2.0 | 5.7 | <0.001 |
| Wheeze in last 12 months without cold (%) | 3.4 | 8.3 | <0.001 |
| Shortness of breath while walking (%) | 11.9 | 19.1 | <0.001 |
| Chronic cough (%) | 2.3 | 5.9 | 0.002 |
| Chronic phlegm (%) | 4.8 | 4.9 | 0.964 |
| COPD* (%) | 14.3 | 37.9 | <0.001 |