Adjusted dosage regimens, total AAT trough concentrations, patient measurements at baseline and after dosage adjustment (in g/l), and difference between both measurements (Δtotal AAT CminSS)
| Patient no | Baseline total AAT CminSS | Adjusted dosage regimen(g/days) | Adjusted dosage regimen(mg/kg/days) | Total AAT CminSS after dose adjustment | Δ total AAT CminSS |
|---|---|---|---|---|---|
| CminSS, expected exogenous minimum AAT concentrations at steady state (SS) conditions. | |||||
| 1 | 0.09 | 4/7 | 62.5/7 | 0.50 | 0.41 |
| 2 | 0.31 | 7/14 | 137/14 | 0.51 | 0.20 |
| 3 | 0.36 | 9/14 | 120/14 | 0.53 | 0.17 |
| 4 | 0.34 | 7/14 | 121/14 | 0.54 | 0.20 |
| 5 | 0.32 | 14/21 | 205/21 | 0.41 | 0.09 |
| 6 | 0.38 | 11/21 | 190/21 | 0.44 | 0.06 |