Association between study diagnoses and anti-Cpn IgG in children at 4 years of age according to sex
| Diagnoses | Boys | Girls | p value† | ||||
|---|---|---|---|---|---|---|---|
| IgG+ | IgG− | OR (95% CI) | IgG+ | IgG− | OR (95% CI) | ||
| *Number of children with diagnosis/total number of children within category (%). | |||||||
| †Test of homogeneity of ORs between sexes. | |||||||
| ‡Statistically significant also when adjusting for multiple testing (p = 0.0026). | |||||||
| §Sensitisation to inhalants = Phadiatop >0.35 kUA/l; sensitisation to foods = fx5 >0.35 kUA/l. | |||||||
| Wheeze at 1 year | 6/85 (7.1)* | 51/735 (6.9) | 1.02 (0.42 to 2.45) | 8/74 (10.8) | 23/669 (3.4) | 3.40 (1.46 to 7.96)‡ | 0.046 |
| Wheeze at 2 years | 12/84 (14.3) | 70/729 (9.6) | 1.57 (0.81 to 3.04) | 10/72 (13.9) | 47/668 (7.0) | 2.13 (1.02 to 4.44) | 0.542 |
| Wheeze at 4 years | 17/85 (20.0) | 150/739 (20.3) | 0.98 (0.56 to 1.72) | 19/74 (25.7) | 99/675 (14.7) | 2.01 (1.14 to 3.54) | 0.075 |
| Asthma | 10/85 (11.8) | 84/736 (11.4) | 1.03 (0.51 to 2.08) | 9/74 (12.2) | 45/675 (6.7) | 1.94 (0.90 to 4.15) | 0.230 |
| Suspected allergic rhinitis | 4/84 (4.8) | 45/734 (6.1) | 0.77 (0.27 to 2.19) | 2/72 (2.8) | 18/665 (2.7) | 1.03 (0.23 to 4.52) | 0.751 |
| Eczema | 12/85 (14.1) | 143/740 (19.3) | 0.69 (0.36 to 1.30) | 16/74 (21.6) | 142/679 (20.9) | 1.04 (0.58 to 1.87) | 0.341 |
| Sensitisation to inhalants§ | 12/85 (14.1) | 142/742 (19.1) | 0.69 (0.37 to 1.31) | 10/74 (13.5) | 75/680 (11.0) | 1.26 (0.62 to 2.56) | 0.217 |
| Sensitisation to foods§ | 8/85 (9.4) | 120/742 (16.2) | 0.54 (0.25 to 1.15) | 16/74 (21.6) | 90/680 (13.2) | 1.81 (0.99 to 3.29) | 0.011 |
| Any IgE sensitisation | 13/85 (15.3) | 201/742 (27.1) | 0.49 (0.26 to 0.90) | 19/74 (25.7) | 138/680 (20.3) | 1.36 (0.78 to 2.36) | 0.013 |