Group A(n = 7) | Controls(n = 14) | p value* | Group B(n = 15) | Controls(n = 30) | p value† | |
---|---|---|---|---|---|---|
Group A, patients without pulmonary fibrosis on the chest radiograph; group B, patients with pulmonary fibrosis on the chest radiograph; Pao2, arterial oxygen tension at room air; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; TLC, total lung capacity; Tlco, carbon monoxide transfer factor; Kco, carbon monoxide transfer coefficient. | ||||||
Comparison with matched controls with sarcoidosis without PH. | ||||||
*Comparison between patients in group A and controls. | ||||||
†Comparison between patients in group B and controls. | ||||||
‡Tlco and Kco were not available in one patient in group A and two patients in group B. | ||||||
Pao2 (kPa) | 8.4 (2.3) | 10.4 (1.1) | 0.024 | 7.9 (1.5) | 10.5 (1.5) | <0.0001 |
FEV1 (ml) | 2141 (481) | 2504 (865) | 0.329 | 1233 (482) | 2030 (794) | 0.001 |
FEV1 (% pred) | 75 (20) | 84 (11) | 0.204 | 38 (18) | 56 (21) | 0.01 |
FEV1/FVC (%) | 75 (8) | 72 (9) | 0.483 | 63 (14) | 67 (17) | 0.449 |
FVC (ml) | 2851 (649) | 3648 (1269) | 0.143 | 2051 (659) | 3105 (1171) | 0.003 |
FVC (% pred) | 82 (18) | 93 (9) | 0.07 | 50 (16) | 71 (23) | 0.004 |
TLC (ml) | 4688 (1022) | 5247 (1312) | 0.348 | 4198 (1109) | 4827 (1465) | 0.165 |
TLC (% pred) | 84 (13) | 92 (13) | 0.235 | 67 (13) | 73 (18) | 0.265 |
Tlco (% pred)‡ | 39 (28) | 86 (20) | 0.0009 | 38 (10) | 57 (19) | 0.002 |
Kco (% pred)‡ | 41 (29) | 88 (18) | 0.0005 | 58 (19) | 77 (22) | 0.01 |