Association between serum leptin concentration and asthma in women aged ⩾20 years according to menopausal status (NHANES III, 1988–1994)
| Leptin quartiles* | Premenopausal (n = 1701) | Postmenopausal (n = 1385) | ||
|---|---|---|---|---|
| OR (95% CI) | p value Wald χ2 | OR (95% CI) | p value Wald χ2 | |
| *For women, quartile 1 is ⩽7.7, quartile 2 is >7.7–⩽13.2, quartile 3 is >13.2–⩽21.9, and quartile 4 is >21.9 μg/l serum leptin. | ||||
| †Adjusted for age, race/ethnicity, educational status, smoking status, cotinine concentration, triceps skinfold thickness, physical activity, and atopy. | ||||
| The interaction between menopausal status and concentrations of serum leptin modelled in quartiles on asthma status was not significant (p (Wald χ2) = 0.39). | ||||
| Quartile 1 (reference)† | 1.00 | 0.048 | 1.00 | 0.114 |
| Quartile 2 | 1.80 (0.51 to 6.35) | 0.60 (0.19 to 1.90) | ||
| Quartile 3 | 1.69 (0.50 to 5.63) | 1.06 (0.40 to 2.76) | ||
| Quartile 4 | 3.56 (1.11 to 11.36) | 2.16 (0.60 to 7.76) | ||