Characteristics of patients with COPD according to the presence or absence of emphysema on HRCT examination
| Emphysema(n = 11) | No emphysema(n = 15) | p value | |
|---|---|---|---|
| NS, not significantly different; BMI, body mass index; MMRC, modified Medical Research Council; 6MWD, 6 minute walk distance; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; FRC, functional residual capacity; Kco, carbon monoxide transfer coefficient; RV, residual volume; Pao2, arterial oxygen tension; Paco2, arterial carbon dioxide tension. | |||
| Data presented as mean (SE); comparisons made using unpaired t test. | |||
| Age (years) | 71 (3) | 70 (2) | NS |
| Sex (M/F) | 10/1 | 12/3 | |
| BMI (kg/m2) | 24.5 (1.2) | 28.1 (0.6) | 0.008 |
| Dyspnoea (MMRC score) | 3 (0.4) | 2 (0.2) | 0.03 |
| 6MWD (m) | 357 (42) | 395 (23) | NS |
| FEV1 (% predicted) | 31.3 (2.6) | 47.1 (3.8) | 0.004 |
| FEV1/FVC (%) | 37.2 (1.9) | 49.47 (2) | 0.0002 |
| FRC (% predicted) | 139.6 (7.0) | 112.5 (4.3) | 0.002 |
| Kco (% predicted) | 31.7 (5.2) | 54.4 (4.3) | 0.002 |
| RV (% predicted) | 152.9 (7.9) | 131.1 (5.8) | 0.03 |
| Pao2 (kPa) | 9.7 (0.4) | 10.2 (0.4) | NS |
| Paco2 (kPa) | 5.6 (0.2) | 5.2 (0.1) | NS |