Asthma and hay fever according to HRT use in 2206 women aged 46–54 years
| No HRT(n = 1666)(%) | HRT(n = 540)(%) | OR (95% CI)* | p value | |
|---|---|---|---|---|
| *From logistic regression models with adjustment for smoking habits, BMI, age, centre, and social class. | ||||
| †Asthma medication and/or asthma attacks in the last 12 months. | ||||
| ‡Wheeze in the last 12 months. | ||||
| §Symptoms included: wheeze, wheeze with shortness of breath, wheeze without cold, waking with tightness in chest, waking with shortness of breath, waking with cough, asthma attacks, current asthma medication. | ||||
| **Waking with tightness in chest or waking with shortness of breath. | ||||
| ††Hay fever or nasal allergies. | ||||
| ‡‡Asthma and hay fever. | ||||
| Asthma† | 7.2 | 10.0 | 1.50 (1.03 to 2.20) | 0.035 |
| Wheeze‡ | 18.7 | 23.1 | 1.54 (1.17 to 2.02) | 0.002 |
| Three or more symptoms§ | 13.3 | 18.5 | 1.62 (1.20 to 2.20) | 0.002 |
| Night symptoms** | 14.2 | 11.8 | 0.85 (0.61 to 1.18) | 0.3 |
| Hay fever†† | 23.0 | 27.4 | 1.47 (1.14 to 1.88) | 0.003 |
| Allergic asthma‡‡ | 3.9 | 5.8 | 1.77 (1.09 to 2.89) | 0.022 |