Occurrence of asthma, bronchial hyperreactivity (BHR), atopy, and bronchodilator treatment in children with SCD and controls
| Asthma status | SCD(n = 80) | Control(n = 80) | Odds ratio (95% CI) | p value |
|---|---|---|---|---|
| “Asthma ever” | 38 (48%) | 18 (22%) | 3.1 (1.5 to 6.8) | 0.002 |
| Atopic | 16 (20%) | 7 (9%) | 2.5 (1.0 to 6.4) | 0.06 |
| Non-atopic | 22 (28%) | 11 (14%) | 2.6 (1.1 to 6.2) | 0.03 |
| “Current asthma” | 33 (41%) | 12 (15%) | 4.5 (1.9 to 10.9) | 0.001 |
| Atopic | 15 (19%) | 5 (6%) | 3.5 (1.2 to 10.6) | 0.03 |
| Non-atopic | 18 (22%) | 7 (9%) | 2.8 (1.1 to 7.2) | 0.03 |
| Atopy | 29 (36%) | 27 (34%) | 1.1 (0.6 to 2.1) | 0.75 |
| Bronchodilator treatment | 11 (14%) | 5 (6%) | 2.5 (0.8 to 8.0) | 0.12 |