Costs per additional patient with relevant improvement in quality of life
| Interventions | Time scale | Year | Costs per additional patient with improved QoL ⩾MCID | QoL measure |
|---|---|---|---|---|
| MCID, minimal clinically important difference; MDI, metered dose inhaler; DPI, dry powder inhaler; QoL, quality of life; SGRQ, St George’s Respiratory Questionnaire; CRQ, Chronic Respiratory Questionnaire.61–64 | ||||
| Tiotropium v ipratropium (MDI)60 | 1 year | 2001 | Euros 1084 | SGRQ total |
| Tiotropium v ipratropium >(44% MDI/56% DPI)60 | 1 year | 2001 | Euros 289 | SGRQ total |
| Salmeterol v placebo59 | 4 months | Not reported | UK £497 | SGRQ total |
| Early treatment with fluticasone >v placebo58 | 1 year | 1998 | US $1674 | CRQ dyspnoea |
| Detection+early treatment with fluticasone v placebo58 | 1 year | 1998 | US $4361 | CRQ dyspnoea |
| Rehabilitation (2 months inpatient and 4 months outpatient) v conventional community care57 | 6 months | 1989 | Can $28993 | CRQ mastery |
| Can $38270 | CRQ emotional | |||
| Can $47548 | CRQ dyspnoea | |||
| Can $51027 | CRQ fatigue | |||