Relative risk (with 95% confidence interval) of lung cancer for men and women in different quintiles of lung function
| Quintile 1 | Quintile 2 | Quintile 3 | Quintile 4 | Quintile 5 | |
|---|---|---|---|---|---|
| All data were merged using a fixed effects model because there was no significant heterogeneity in data across the studies (p>0.10). | |||||
| Men | |||||
| Hole10 | 2.53 (1.68 to 3.82) | 1.93 (1.27 to 2.94) | 1.80 (1.17 to 2.77) | 1.36 (0.86 to 2.16) | 1.00 |
| Kuller11 | 3.56 (1.02 to 12.43) | 2.44 (1.17 to 5.05) | 2.80 (1.32 to 5.93) | 0.50 (0.11 to 2.34) | 1.00 |
| Mannino12 | 3.16 (1.20 to 8.33) | 1.03 (0.35 to 3.06) | 1.11 (0.35 to 3.46) | 0.94 (0.29 to 3.10) | 1.00 |
| Van Den Eeden13 | 1.86 (1.32 to 2.64) | 1.60 (1.35 to 1.90) | 1.45 (1.20 to 1.75) | 1.34 (1.04 to 1.72) | 1.00 |
| Pooled summary | 2.23 (1.73 to 2.86) | 1.67 (1.42 to 1.93) | 1.54 (1.30 to 1.82) | 1.30 (1.05 to 1.62) | 1.00 |
| Women | |||||
| Hole10 | 4.39 (1.86 to 10.38) | 4.14 (1.73 to 9.87) | 4.01 (1.68 to 9.58) | 3.63 (1.51 to 8.76) | 1.00 |
| Mannino12 | 5.99 (0.75 to 47.94) | 8.58 (1.09 to 67.36) | 8.76 (1.09 to 70.11) | 1.08 (0.07 to 17.29) | 1.00 |
| Van Den Eeden13 | 1.95 (0.32 to 11.70) | 1.45 (0.27 to 7.69) | 1.80 (0.52 to 6.30) | 1.55 (0.41 to 5.81) | 1.00 |
| Pooled summary | 3.97 (1.93 to 8.25) | 3.71 (1.80 to 7.69) | 3.46 (1.75 to 6.75) | 2.64 (1.30 to 5.31) | 1.00 |
| Pooled summary for men and women | 2.36 (1.88 to 3.00) | 1.72 (1.48 to 1.99) | 1.62 (1.38 to 1.90) | 1.38 (1.13 to 1.70) | 1.00 |