Risk of suffering from moderate to severe lung disease in patients with class I or II mutations on both chromosomes
| No of subjects(n = 74) | Genotype I–II/I–II n (%) | Odds ratio*(95% CI) | Odds ratio†(95% CI) | |
|---|---|---|---|---|
| FVC, forced vital capacity; FEV1, forced expiratory volume in 1 second. | ||||
| *Calculated by univariate logistic regression models (95% CI). | ||||
| †Adjusted for pancreatic insufficiency. | ||||
| FVC | ||||
| ⩾60% | 49 | 16 (33%) | 1 | 1 |
| <60% | 25 | 21 (84%) | 10.83 (3.18 to 36.84) | 7.12 (1.25 to 40.46) |
| FEV1 | ||||
| ⩾60% | 37 | 8 (22%) | 1 | 1 |
| <60% | 37 | 29 (78%) | 13.14 (4.34 to 39.75) | 8.74 (1.89 to 40.83) |