Table 2

 Prevalence of asthma and allergies among German children living in three different areas: 1992–2001

1992/3 n (%)1993/4 n (%)1994/5 n (%)1996/7 n (%)1998/9 n (%)2000/1 n (%)Time trends
Crude OR per year(95% CI)Adjusted* OR per year(95% CI)
*Adjusted for sex, family history of atopic diseases, socioeconomic status, breast feeding, passive smoking, number of siblings, place of living, dampness.
†SX1: specific IgE against a panel of aeroallergens (mixed grass pollen, birch pollen, mugwort pollen, Dermatophagoides pteronyssinus, cat dander, dog dander, Cladosporiumherbarum).
QuestionnaireN = 761N = 731N = 670N = 717N = 739N = 772
Diagnoses
    Asthma37 (4.9%)35 (4.8%)20 (3.0%)31 (4.3%)30 (4.1%)43 (5.6%)1.02 (0.97 to 1.07)1.00 (0.95 to 1.06)
    Hay fever58 (7.6%)47 (6.4%)52 (7.8%)58 (8.1%)62 (8.4%)70 (9.1%)1.03 (0.995 to 1.07)1.02 (0.97 to 1.06)
Symptoms
    Wheeze ever233 (30.6%)228 (31.2%)205 (30.6%)201 (28.0%)205 (27.7%)240 (31.1%)0.97 (0.94 to 0.99)0.95 (0.93 to 0.98)
    Wheeze in past 12 months72 (9.5%)80 (10.9%)58 (8.7%)68 (9.5%)73 (9.9%)81 (10.5%)1.00 (0.97 to 1.03)0.99 (0.95 to 1.03)
    Runny nose/itchy eyes70 (9.2%)69 (9.4%)70 (10.4%)59 (8.2%)58 (7.8%)79 (10.2%)1.00 (0.96 to 1.03)0.98 (0.94 to 1.02)
Serum analysesN = 649N = 606N = 600N = 497N = 552N = 479
    Specific IgE (SX1)†221 (34.1%)181 (29.9%)218 (36.3%)181 (36.4%)197 (35.7%)166 (34.7%)1.02 (0.99 to 1.04)0.99 (0.97 to 1.02)