Table 1

 Characteristics of the study populations

1992/31993/41994/51996/71998/92000/1
*All children with known sex, age and residence for at least two years in study area.
†Proportion of children participating in blood sampling of those invited to participate (these were random subsamples after 1995).
‡High socioeconomic status (SES) defined as mother, father, or both having at least 13 years of school education.
¶Environmental tobacco smoke (ETS) defined as any passive smoke exposure in the home.
§Exclusive breast feeding for at least 4 months.
Addressed141013091402151315001548
Questionnaires completed107710791078117111971160
Participation rate76.4%82.4%76.9%77.3%79.8%74.9%
Study sample*919955930103010361070
Serum samples798763832674722653
Participation in blood sampling†86.8%79.9%89.5%78.4%82.4%93.4%
Mean (SD) age (years)10.4 (0.6)10.3 (0.6)10.3 (0.6)10.2 (0.6)10.2 (0.6)10.2 (0.5)
Sex (female)467 (51%)474 (50%)450 (48%)524 (51%)519 (50%)503 (47%)
German nationality761 (83%)731 (77%)670 (72%)717 (70%)739 (71%)772 (72%)
German children only
    SES high‡145 (19%)196 (27%)145 (22%)170 (24%)194 (26%)212 (27%)
    ETS¶405 (53%)360 (49%)348 (52%)360 (50%)366 (50%)388 (50%)
No of siblings
    ⩾2297 (39%)264 (36%)251 (37%)263 (37%)278 (38%)298 (39%)
Familial history of asthma, atopic eczema or hay fever221 (29%)243 (33%)239 (36%)241 (34%)269 (36%)283 (37%)
Breast feeding§158 (21%)149 (20%)174 (26%)220 (31%)246 (33%)255 (33%)