Summary of defects in the immune defences
| Immunodeficiency | Clinical features |
|---|---|
| MBL deficiency heterozygote | Susceptibility to Burkholderia complex |
| Specific pneumococcal antibody deficiency | Recurrent Streptococcus pneumoniae infections |
| T cell dysregulation | As seen in adult onset antibody deficiency |
| Arg131/Arg131 homozygous allotype for CD32 | Associated with poor outcome from Streptococcus pneumoniae bacteraemia |