Parameter | FEV1 groups | p value | |
---|---|---|---|
Responders | Non-responders | ||
PEF, peak expiratory flow; TPpeak, peak transpulmonary pressure during a forced expiratory manoeuvre; TLC, total lung capacity; RV, residual volume; RV/TLC, RV/TLC ratio; Rle, expiratory lung resistance; Rli, inspiratory lung resistance; coefficient Pel, elastic recoil pressure at TLC/TLC; FVC, forced expiratory vital capacity; FEV1, forced expired volume in the first second of forced expired manoeuvre; NFEV1, FEV1 obtained using no compression method; DFEV1, (NFEV1 − FEV1)/FEV1. | |||
PEF (l/s) | 2.96 (0.26) | 2.93 (0.19) | >0.91 |
TPpeak (cm H2O) | 148 (19.5) | 92 (27.1) | 0.11 |
TLC (l) | 9.4 (1.4) | 9.8 (0.8) | >0.44 |
RV (l) | 6.2 (1.3) | 6.5 (1.1) | >0.59 |
RV/TLC (%) | 66 (6) | 66 (8) | >0.90 |
Rle (cm H2O/l/s) | 26 (19.4) | 25 (17.0) | >0.94 |
Rli (cm H2O/l/s) | 5 (2.6) | 5 (1.8) | >0.80 |
Coefficient Pel (cm H2O/l) | 1.14 (0.35) | 1.14 (0.47) | >0.99 |
FVC (l) | 2.2 (0.60) | 2.5 (0.89) | >0.24 |
FEV1 (l) | 0.84 (0.26) | 0.90 (0.23) | >0.50 |
NFEV1 (l) | 1.56 (0.39) | 1.30 (0.31) | 0.06 |
FEV1/FVC (%) | 39 (7.5) | 38 (8.2) | >0.73 |
DFEV1 (% change from baseline) | 98 (58) | 48 (30) | 0.01 |