Lung function and inflammatory parameters in BAL fluid of subjects with and without infection
| Parameter | Uninfected(N = 15 children,N = 17 visits) | Infected†(N = 9 children,N = 10 visits) | p value |
|---|---|---|---|
| TCC, total cell count; IL, interleukin; LTB4, leukotriene B4; Raw, tissue resistance; Grs, tissue damping; Hrs, tissue elastance; η, ratio of damping to elastance. | |||
| Values are median (IQR). | |||
| *p<0.05. | |||
| †Infection was categorised as >104 cfu/ml. | |||
| Lung function data corrected for body length and number of visits. | |||
| Age (years) | 1.58 (1.12 to 2.91) | 1.55 (1.11 to 2.51) | NS |
| TCC/ml (×106) | 0.34 (0.23 to 0.47) | 1.29 (0.27 to 6.01) | 0.098 |
| Neutrophils (%) | 17.3 (8.75 to 29.10) | 52.0 (37.85, 81.00) | <0.001* |
| Neutrophils/ml (×103) | 60.03 (38.92 to 91.34) | 667.58 (57.52 to 5341.48) | 0.04* |
| IL-8 (ng/ml) | 0.36 (0.18 to 1.42) | 1.36 (0.16 to 1.91) | NS |
| LTB4 (pg/ml) | 6.23 (2.4 to 12.92) | 6.53 (4.97 to 25.88) | NS |
| Symptomatic (% visits) | 17% | 80% | NS |
| Raw | 14.32 (9.86 to 20.81) | 12.85 (10.03 to 22.80) | NS |
| Grs | 27.18 (16.8 to 38.3) | 38.26 (25.87 to 44.13) | NS |
| Hrs | 115.3 (77.4 to 144.24) | 142.78 (110.64 to 175.82) | NS |
| η | 0.26 (0.19 to 0.32) | 0.25 (0.14 to 0.31) | NS |