Demographic characteristics of patients (according to GOCA stratification24)
| ARDS(n = 41) | At risk(n = 12) | p value | |
|---|---|---|---|
| PEEP, positive end expiratory pressure; APACHE, Acute Physiology and Chronic Health Evaluation; ARDS, acute respiratory distress syndrome; LIS, lung injury score; SAPS, Simplified Acute Physiology Score. | |||
| Gas exchange | |||
| Mean (SD) P:F ratio (kPa) | 16.8 (8.2) | 39.9 (10.4) | 0.001 |
| Pao2/FIo2 >40 kPa | 0 | 9 | |
| Pao2/FIo2 26.8–40 kPa | 14 | 2 | 0.001 |
| Pao2/FIo2 13.46–26.8 kPa | 18 | 1 | |
| Pao2/FIo2 <13.46 kPa | 9 | 0 | |
| Spontaneous breathing, no PEEP | 0 | 0 | |
| Assisted breathing, PEEP 0–5 cm H2O | 14 | 8 | NS |
| Assisted breathing, PEEP 6–10 cm H2O | 18 | 2 | |
| Assisted breathing, PEEP >10 cm H2O | 9 | 1 | |
| Organ failure (non-pulmonary) | |||
| 0 organ | 2 | 2 | |
| 1 organ | 22 | 6 | NS |
| 2 organs | 14 | 2 | |
| 3 organs | 3 | 0 | |
| Cause | |||
| Unknown | 0 | 0 | |
| Indirect lung injury | 17 | 8 | NS |
| Direct lung injury | 24 | 4 | |
| Other parameters | |||
| Age | 62 (18–93) | 68 (29–78) | NS |
| APACHE II | 22.1 (9.3) | 21.23 (12.2) | NS |
| SAPS II | 42.6 (15.8) | 42.8 (14.3) | NS |
| LIS | 2.7 (0.6) | 1.15 (0.7) | 0.01 |
| Mortality | 51% | 46% | NS |