Table 3

 Relationship of respiratory symptoms, lung function, and conditions to occupational exposures

N‡Exposed§Not exposed§Odds ratio(95% CI)†
Tlco, carbon monoxide lung transfer factor.
*p<0.05.
†Odds ratios (and 95% CI) were adjusted by age, sex, smoking status, and pack years. ‡Number of subjects with respiratory symptoms or conditions.
§Proportion of subjects with specific condition with and without exposure.
Biological dustn = 484n = 729
    Morning cough19591 (18.9)104 (14.3)1.41 (1.03 to 1.93)*
    Chronic cough12057 (11.3)63 (8.96)1.40 (0.96 to 2.06)
    Morning phlegm9040 (8.2)50 (6.9)1.25 (0.80 to 1.94)
    Chronic bronchitis4926 (5.5)23 (3.1)1.74 (0.97 to 3.11)
    Dyspnoea277130 (26.9)147 (20.2)1.35 (1.01 to 1.79)*
    Mild airflow obstruction226102 (21.1)124 (17.0)1.30 (0.96 to 1.76)
    Moderate airflow obstruction8338 (7.9)45 (6.2)1.27 (0.80 to 2.00)
    Tlco <80% predicted15362 (13.1)91 (12.5)1.04 (0.80 to 1.34)
    Chronic obstructive bronchitis2215 (3.1)7 (1.0)3.19 (1.27 to 7.97)*
    Emphysema (symptomatic)2919 (4.0)10 (1.4)3.18 (1.41 to 7.13)*
    Emphysema (asymptomatic)5630 (6.2)26 (3.6)1.89 (1.07 to 3.34)*
    COPD4226 (5.4)16 (2.2)2.70 (1.39 to 5.23)*
Mineral dustn = 399n = 814
    Morning cough19567 (16.8)128 (15.7)1.06 (0.75 to 1.49)
    Chronic cough12042 (10.5)78 (9.6)1.08 (0.71 to 1.65)
    Morning phlegm9040 (10.0)50 (6.1)1.44 (0.90 to 2.28)
    Chronic bronchitis4921 (5.3)28 (3.4)1.32 (0.71 to 2.44)
    Dyspnoea27792 (23.1)185 (22.7)1.22 (0.89 to 1.67)
    Mild airflow obstruction22679 (19.8)147 (18.1)0.93 (0.67 to 1.29)
    Moderate airflow obstruction8325 (6.3)58 (7.1)0.71 (0.42 to 1.19)
    Tlco <80% predicted15350 (12.8)102 (12.7)0.85 (0.64 to 1.13)
    Chronic obstructive bronchitis229 (2.3)13 (1.6)1.40 (0.56 to 3.51)
    Emphysema (symptomatic)2911 (2.8)18 (2.3)1.07 (0.46 to 2.45)
    Emphysema (asymptomatic)5620 (5.0)36 (4.4)0.96 (0.52 to 1.79)
    COPD4216 (4.1)26 (3.3)1.13 (0.57 to 2.27)
Gases and fumesn = 663n = 550
    Morning cough195116 (17.5)79 (14.4)1.27 (0.92 to 1.76)
    Chronic cough12070 (10.6)50 (9.1)1.16 (0.79 to 1.72)
    Morning phlegm9060 (9.1)30 (5.5)1.59 (1.00 to 2.53)*
    Chronic bronchitis4931 (4.7)18 (3.3)1.31 (0.72 to 2.40)
    Dyspnoea277154 (23.2)123 (22.4)1.09 (0.82 to 1.45)
    Mild airflow obstruction226124 (18.7)102 (18.6)0.92 (0.67 to 1.24)
    Moderate airflow obstruction8345 (6.8)38 (6.9)0.71 (0.42 to 1.19)
    Tlco <80% predicted15384 (13.0)68 (12.5)1.03 (0.80 to 1.33)
    Chronic obstructive bronchitis2217 (2.6)5 (0.9)2.81 (1.01 to 7.79)*
    Emphysema (symptomatic)2918 (2.7)11 (2.0)1.26 (0.57 to 2.80)
    Emphysema (asymptomatic)5632 (4.8)24 (4.4)0.96 (0.52 to 1.79)
    COPD4228 (4.2)14 (2.6)1.63 (0.83 to 3.22)