Correlation coefficients (r values) between sputum markers and airway wall thickness or post-bronchodilator pulmonary function
| MMP-9 levels | TIMP-1 levels | Molar ratio of MMP-9/TIMP-1 | |
|---|---|---|---|
| WA/BSA, wall area/body surface area; WA%, 100×WA/outer area of the bronchus; T, absolute airway thickness; FEF25–75%, mid-forced expiratory flow; MEF25%, maximum expiratory flow at the quartile of lung volume; MMP, matrix metalloproteinase; TIMP, tissue inhibitor of metalloproteinase. | |||
| *p<0.05, †p<0.03, ‡p<0.003, §p<0.01. | |||
| WA/BSA (mm2/m2) | 0.24 | 0.42* | −0.12 |
| WA% | −0.47† | 0.15 | −0.64‡ |
| T/√BSA (mm/m) | −0.15 | 0.41* | −0.54§ |
| FEV1 (%pred) | 0.24 | 0.12 | 0.25 |
| FEF25–75% (%pred) | 0.11 | −0.26 | 0.41* |
| MEF25% (%pred) | 0.20 | −0.21 | 0.42* |