Nitric oxide synthase enzymes
| NOS isoforms | Numerical designation | Other designation | Expression | Regulation | NO output | Chromosome |
|---|---|---|---|---|---|---|
| NO, nitric oxide; NOS, nitric oxide synthase; nNOS, neural nitric oxide synthase; iNOS, inducible nitric oxide synthase; eNOS, endothelial nitric oxide synthase; CaM, calmodulin. | ||||||
| Type I | 1 | nNOS | Constitutive | Calcium/CaM | Low (picomol) | 12 |
| Type II | 2 | iNOS | Inducible | Induced by cytokines, endotoxin, and oxidants | High (nanomol) | 17 |
| Type III | 3 | eNOS | Constitutive | Calcium/CaM | Low (picomol) | 7 |