Table 2

Details of lung samples used for isolated human pulmonary artery experiments and characteristics of the patients from whom the tissue was obtained

PatientAge (years)SexMedical historyMedicationAnaesthesia and analgesiaPeptide studied
Chemical nameClass of drugAnaesthetic regimenAnalgesic regimen
NSAID = non-steroidal anti-inflammatory drug; HRT = hormone replacement therapy.
All patients received cefamandole in addition to one of the following anaesthetic regimens:
 C: inhaled anaesthetic: isofluorane + nitrous oxide, iv anaesthetic: propofol, non-depolarising muscle relaxant: atracurium;
 I: inhaled anaesthetic: isofluorane + nitrous oxide, iv anaesthetic: propofol, non-depolarising muscle relaxant: vencuronium bromide
and the following analgesic regimen:
 G: morphine + fentanyl.
RDJh275MNoneIGgUII
RDJh365MArthritisDiclofenac sodiumNSAIDIGgUII
RDJh664MGlaucoma mildDihydrocodeineOpioid analgesicCGgUII/hUII
Asthma
RDJh768MNoneIGgUII/hUII
RDJh865FAsthmaSalbutamolβ2 agonistIGhUII
BeclomethasoneCorticosteroid
Disodium etridronateBone metabolism inhibitor
RDJh959FAsthma BronchitisConjugated oestrogenHRTIGgUII/hUII
Salbutamolβ2 agonist
Salmeterolβ2 agonist
PrednisoloneCorticosteroid
RDJh1078MCoronary heart disease PneumoconiosisAtenololβ1 antagonistIGhUII/ET-1/ET-3
PravastatinStatin
Acetylsalicylic acidNon-opioid analgesic
LoratidineAntihistamine
RDJh1171MCOPDDalteparinHeparinIGET-1/ET-3
CefotaximeCephalosporin
ParacetamolNon-opioid analgesic
DihydrocodeineOpioid analgesic
RDJh1265MHypothyroidismThyroxineThyroid hormoneCGET-1/ET-3
Chronic diarrhoeaSulphasalazineAnti-diarrhoea agent
RDJh1352MHypertensionAtenololβ1 antagonistIGET-1/ET-3
AmlodipineCalcium antagonist
BendrofluazideDiuretic
DiazepamAnxiolytic agent