ED50 values of iodo-resiniferatoxin and capsazepine in inhibiting cough induced by capsaicin and citric acid in guinea pigs
| Iodo-resiniferatoxin | Capsazepine | |||
|---|---|---|---|---|
| Aerosol(nM) | Intraperitoneal(nmol/kg) | Aerosol(nM) | Intraperitoneal(nmol/kg) | |
| Data are mean (SE) of at least eight experiments. | ||||
| *p<0.01 v capsazepine. | ||||
| Capsaicin | 284 (92)* | 29 (9)* | 34280 (867) | 860 (27) |
| Citric acid | 84 (19)* | 16 (4)* | 12840 (1621) | 150 (6) |