Resting and end exercise ventilatory pattern, metabolic and cardiac variables after placebo and salbutamol
| After placebo (mean (SE) exercise time 316 (52) s) | After salbutamol (mean (SE) exercise time 330 (35) s) | |||
|---|---|---|---|---|
| Rest | End exercise | Rest | End exercise | |
| Values are expressed as mean (SE). | ||||
| *p<0.05 (salbutamol v placebo). | ||||
| Vt (l) | 0.805 (0.052) | 1.325 (0.074) | 0.875 (0.065) | 1.371 (0.064) |
| fr (breaths/min) | 23.9 (2.2) | 34.3 (1.8) | 25.2 (2.2) | 32.7 (2.1) |
| Ti (s) | 1.17 (0.07) | 0.82 (0.05) | 1.18 (0.08) | 0.90 (0.07) |
| Te (s) | 1.99 (0.17) | 1.08 (0.06) | 1.94 (0.21) | 1.26 (0.13)* |
| Vt/Ti (l/s) | 0.71 (0.04) | 1.71 (0.10) | 0.75 (0.04) | 1.65 (0.10) |
| Vt/Te (l/s) | 0.43 (0.02) | 1.30 (0.07) | 0.48 (0.03)* | 1.25 (0.09) |
| V˙e (l/min) | 15.9 (0.8) | 43.7 (2.5) | 17.35 (0.99)* | 41.6 (2.8) |
| V˙o2 (l/min) | 0.34 (0.02) | 0.93 (0.05) | 0.33 (0.02) | 0.95 (0.05) |
| V˙co2 (l/min) | 0.29 (0.02) | 0.87 (0.05) | 0.28 (0.01) | 0.91 (0.06) |
| RER | 0.84 (0.02) | 0.93 (0.02) | 0.86 (0.03) | 0.96 (0.03)* |
| HR (beats/min) | 91.1 (3.6) | 114.4 (4.4) | 89.1 (2.0) | 116.2 (4.1) |
| V˙o2/HR (ml/beat) | 3.6 (0.2) | 8.7 (0.4) | 3.7 (0.2) | 8.3 (0.6) |
| Sao2 (%) | 96.0 (0.6) | 93.6 (0.5) | 96.2 (0.5) | 94.5 (0.6) |
| Breathlessness | 0.75 (0.25) | 5.61 (0.48) | 1.00 (0.30) | 6.28 (0.52) |
| Leg effort | 0.72 (0.24) | 5.33 (0.56) | 0.83 (0.23) | 6.03 (0.68) |