Haemodynamic variables 2 years after mitral valve replacement (baseline) and after long term epoprostenol treatment
| Baseline | Epoprostenol | ||
|---|---|---|---|
| 6 months* | 17 months† | ||
| *Epoprostenol dose 24 ng/kg/min. | |||
| †Epoprostenol dose 26 ng/kg/min. | |||
| ‡Thrombosis of the anterior leaflet of the St Jude valve led to mild increases in pulmonary artery occlusion pressure at 6 months and 17 months after epoprostenol was started. | |||
| Mean systemic arterial pressure (mm Hg) | 83 | 83 | 90 |
| Mean right atrial pressure (mm Hg) | 12 | 16 | 16 |
| Mean pulmonary artery pressure (mm Hg) | 65 | 55 | 57 |
| Cardiac output (l/min) | 2.2 | 2.9 | 3.2 |
| Pulmonary artery occlusion pressure (mm Hg) | 12 | 16‡ | 18‡ |
| Left ventricular end diastolic pressure (mm Hg) | 12 | 7 | – |
| Pulmonary vascular resistance (dyne.s/cm5) | 1560 | 1072 | 999 |