Summary of patient characteristics
| All (N = 116) | “Home” (N = 47) | “Hospital” (N = 51) | “Both” (N = 18) | |
|---|---|---|---|---|
| *Including two patients with methicillin resistant Staphylococcus aureus. | ||||
| Mean (range) age (years) | 26 (16–47) | 26 (17–43) | 26 (16–47) | 25 (19–42) |
| Male/female (%) | 50.0/50.0 | 36.2/63.8 | 58.8/41.2 | 61.1/38.9 |
| Infecting micro-organism (N (%)) | ||||
| Pseudomonas aeruginosa | 103 (88.9) | 43 (91.5) | 42 (82.4) | 18 (100.0) |
| Burkholderia cepacia | 18 (15.5) | 6 (12.8) | 9 (17.6) | 3 (16.7) |
| Other Pseudomonas spp | 2 (1.7) | 0 | 2 (3.9) | 0 |
| Staphylococcus aureus* | 17 (14.7) | 8 (17.0) | 7 (13.7) | 2 (11.1) |
| Other | 51 (44.0) | 19 (40.4) | 24 (47.1) | 8 (44.4) |
| Concomitant treatment (N (%)) | ||||
| Nebulised rhDNase | 75 (64.7) | 30 (63.8) | 32 (62.7) | 13 (72.2) |
| Nebulised colistin | 58 (50) | 26 (55.3) | 21 (41.2) | 11 (61.1) |
| Nebulised gentamicin | 9 (7.8) | 6 (12.8) | 2 (3.9) | 1 (5.6) |
| Nebulised tobramycin | 2 (1.7) | 2 (4.3) | 0 | 0 |
| Oral antibiotics | 104 (89.7) | 43 (91.5) | 45 (88.2) | 16 (88.9) |
| Inhaled/nebulised corticosteroids | 109 (94.0) | 45 (95.7) | 48 (94.1) | 16 (88.9) |
| Regular oral corticosteroids | 12 (10.3) | 5 (10.6) | 5 (9.8) | 2 (11.1) |
| Inhaled/nebulised bronchodilators | 113 (97.4) | 44 (93.6) | 51 (100.0) | 18 (100.0) |
| Aminophylline, theophylline, salbutamol | 73 (62.9) | 26 (55.3) | 36 (70.6) | 11 (61.1) |
| Diabetes (N (%)) | ||||
| Yes | 31 (26.7) | 14 (29.8) | 15 (29.4) | 2 (11.1) |
| Smoking (N (%)) | N = 101 | N = 39 | N = 47 | N = 15 |
| Yes | 13 (12.9) | 6 (15.4) | 6 (12.8) | 1 (6.7) |
| Pregnancy (N (%)) | N = 56 | N = 29 | N = 21 | N = 6 |
| Yes | 4 (7.1) | 1 (3.4) | 2 (9.5) | 1 (16.7) |