Table 3

Univariate and multivariable analysis of overall survival for patients with non-localised* NSCLC according to age, sex, histology, stage, comorbidity, and treatment

	Age <60	Age 60–69	Age 70–79	Age 80+	All ages
Total (n)	710	848	694	128	2380
Alive at 1 year (n)	219	219	146	14	598
Relative 1 year survival (%)	31%	26%	22%	13%	26%

	Overall 1 year survival (%) and univariate p values								Multivariable
	%	p value	%	p value	%	p value	%	p value	HR	p value
HR = hazard ratio for death; RT = radiotherapy.
*Stage III or IV.
†Reference category.
Age
<60	31								0.93	0.2
60–69†			26						1
70–79					21				1.05	0.3
80+							11		1.14	0.2
Sex
Female‡	32		20		11		14		1
Male	30	0.6	27	0.08	23	0.06	10	0.9	1.04	0.5
Histology
Squamous cell‡	35		29		28		12		1
Adenocarcinoma	28		28		18		13		1.07	0.2
Large cell undifferentiated	29	0.3	20	0.08	14	0.01	8	0.6	1.03	0.6
Stage
III‡	41		35		28		13		1
IV	19	<0.001	13	<0.001	10	<0.001	9	0.7	1.14	0.01
Comorbidity
0‡	31		25		23		–		1
1	31		29		22		–		1.01	0.8
2+	25	0.4	25	0.6	19	0.5	–		1.05	0.4
Treatment
RT‡	28		29		28		–		1
Surgery (±RT)	55		49		37		–		0.69	<0.001
Chemo (±RT)	39		35		38		–		0.90	0.2
Other/none	9	<0.001	8	<0.001	8	<0.001	–		1.13	0.03