Comparison of clinical measures in CF and control subjects divided into children/adolescent and adult groups
| Clinical measures | CF | Control | p value | ||
|---|---|---|---|---|---|
| N | Mean (SE) | N | Mean (SE) | ||
| *Defined as 5–18 years for females and 5–20 years for males. | |||||
| †Defined as >18 years for females and >20 years for males. | |||||
| ‡Adjusted for location of data collection to account for the different questionnaires used between the two sites. | |||||
| Children/adolescents* | |||||
| Body cell mass (g) | 89 | 16.1 (0.8) | 105 | 19.3 (0.8) | 0.007 |
| Calcium intake (g) | 49 | 1372 (84) | 69 | 933 (71) | <0.001 |
| Difference from recommended caloric intake (%) | 49 | 60.3 (2.9) | 69 | 52.2 (2.4) | 0.04 |
| 25-hydroxy vitamin D (nmol/l) | 93 | 60.9 (1.7) | 93 | 64.9 (1.7) | 0.09 |
| 1, 25-hydroxy vitamin D (pmol/l) | 93 | 93.6 (4.5) | 85 | 127.3 (4.7) | <0.001 |
| Inhaled corticosteroids (µg/kg/day) | 93 | 38.6 (2.7) | 107 | 2.0 (2.5) | <0.001 |
| Oral corticosteroids (mg/kg/day) | 93 | 0.22 (0.04) | 107 | 0.00 (0.04) | <0.001 |
| CRP (mg/l) | 91 | 4.6 (0.6) | 95 | 2.8 (0.6) | 0.03 |
| Activity questionnaire score‡ | 53 | 2.9 (0.1) | 83 | 2.8 (0.1) | 0.41 |
| Hours of physical activity‡ | 43 | 16.7 (1.8) | 70 | 13.1 (1.4) | 0.12 |
| Ratio of physical/sedentary activity‡ | 43 | 3.7 (1.4) | 70 | 2.3 (1.1) | 0.44 |
| Adults† | |||||
| Body cell mass (g) | 36 | 23.2 (0.5) | 32 | 24.3 (0.5) | 0.14 |
| Calcium intake (g) | 39 | 1672 (122) | 29 | 1083 (142) | 0.003 |
| Difference from recommended caloric intake (%) | 39 | 65.4 (2.8) | 29 | 50.8 (3.2) | 0.001 |
| 25-hydroxy vitamin D (nmol/l) | 48 | 54.7 (2.9) | 41 | 59.6 (3.2) | 0.26 |
| 1, 25-hydroxy vitamin D (pmol/l) | 44 | 91.6 (7.5) | 39 | 114.0 (8.0) | 0.05 |
| Inhaled corticosteroids (µg/kg/day) | 45 | 43.9 (5.3) | 42 | 0.06 (5.2) | <0.001 |
| Oral corticosteroids (mg/kg/day) | 45 | 0.24 (0.05) | 42 | 0.01 (0.05) | <0.001 |
| CRP (mg/l) | 49 | 11.5 (1.4) | 42 | 2.9 (1.5) | <0.001 |
| Activity questionnaire score‡ | 41 | 3.2 (0.1) | 38 | 3.7 (0.1) | 0.005 |
| Hours of physical activity‡ | 38 | 30.6 (4.1) | 38 | 53.2 (4.1) | <0.001 |
| Ratio of physical/sedentary activity‡ | 38 | 6.6 (2.3) | 38 | 8.9 (2.3) | 0.48 |