Mean (SD) characteristics of Mexican healthy subjects and those with idiopathic pulmonary fibrosis (IPF), pigeon breeders’ disease (PBD), and subjects exposed to avian antigen but without PBD (EA)
| Healthy subjects | IPF | PBD | EA | p value* | |
|---|---|---|---|---|---|
| FVC = forced vital capacity; FEV1 = forced expiratory volume in 1 second; Pao2 = arterial oxygen tension; Tlco = carbon monoxide transfer factor; BAL = bronchoalveolar lavage fluid. | |||||
| *IPF group v PBD group. | |||||
| †Time elapsed to first visit is the time elapsed from the beginning of the symptoms to first visit. | |||||
| ‡Absolute ratio. | |||||
| ¶Normal values at Mexico City altitude are 8.9 (0.4) kPa. | |||||
| Sex (F/M) | 78/245 | 32/62 | 115/0 | 71/19 | |
| Age (years) | 33.2 (9.8) | 62.1 (10.0) | 43.9 (13.6) | 35.0 (8.7) | <0.001 |
| Time elapsed to first visit (months)† | 29.8 (22.8) | 21.0 (21.5) | <0.05 | ||
| FVC (% predicted) | 61.8 (19.1) | 56.2 (20.3) | <0.05 | ||
| FEV1 (% predicted) | 65.6 (18.8) | 59.6 (19.9) | NS | ||
| FEV1/FVC (%)‡ | 93.5 (12.5) | 91.8 (8.8) | NS | ||
| Pao2 (kPa)¶ | 6.6 (1.5) | 7.1 (1.4) | <0.01 | ||
| Tlco(%) | 49.4 (12.2) | 51.7 (18.2) | NS | ||
| % BAL macrophages | 77.3 (7.9) | 35.6 (20.2) | <0.001 | ||
| % BAL lymphocytes | 17.6 (7.0) | 62.2 (20.7) | <0.001 | ||
| % BAL neutrophils | 3.4 (3.7) | 1.4 (2.8) | <0.01 | ||
| % BAL eosinophils | 1.7 (2.1) | 0.8 (1.1) | <0.05 | ||