Characteristics of study subjects
| Characteristic | Healthy subjects | Asthmatics | ||
|---|---|---|---|---|
| Children (n = 50) | Adults (n = 50) | Children (n = 33) | Adults (n = 28) | |
| Data are shown as mean (SE) values. | ||||
| BDP = beclomethasone dipropionate; BUD = budesonide; FEV1 = forced expiratory volume in 1 second; FVC = forced vital capacity; MEF = mid expiratory flow rate. | ||||
| Age (years) | 8.7 (0.4) | 37.6 (1.6) | 8.9 (0.4) | 40.4 (2.9) |
| Sex (M/F) | 24/26 | 14/36 | 22/11 | 16/12 |
| FEV1 (% predicted) | 98.7 (1.9) | 107.3 (1.8) | 107.3 (2.5) | 95.1 (2.8) |
| FVC (% predicted) | 86.6 (1.5) | 104.5 (1.9) | 97.4 (2.7) | 98.7 (2.4) |
| MEF50 (% predicted) | 102.3 (3.7) | 99.3 (3.1) | 90.3 (3.4) | 72.1 (3.9) |
| MEF25-75 (% predicted) | 113.9 (3.4) | 100.7 (2.9) | 97.3 (3.8) | 75.9 (4.1) |
| Inhaled corticosteroids (μg/day) | None | None | BDP: 250–500 | BDP: 500–1000 |
| BUD: 200–400 | BUD: 400–800 | |||