Eligibility status by pulmonary function results (n=328)
| Eligible (n=55) | Ineligible (n=226) | Declined (n=47) | |
|---|---|---|---|
| FEV1=forced expiratory volume in 1 second; FVC=forced vital capacity; FRC=functional residual capacity; RV=residual volume; TLC=total lung capacity; Tlco=carbon monoxide transfer factor; MIP=maximum inspiratory pressure; MEP=maximum expiratory pressure; Pao2, Paco2=arterial oxygen and carbon dioxide tensions; Sao2=arterial oxygen saturation. | |||
| Values are mean (SE). | |||
| *MIP and MEP only available from rehabilitation and baseline datasets; no screening data available. | |||
| Age (years) | 64.9 (0.91) | 64.1 (0.53) | 64.1 (1.12) |
| Sex (M/F) | 33/22 | 138/88 | 28/19 |
| FEV1 (observed) | 0.7 (0.03) | 0.8 (0.03) | 0.9 (0.06) |
| FEV1 (% predicted) | 32 (1.38) | 34 (1.07) | 36 (2.39) |
| FVC (observed) | 2.5 (0.12) | 2.5 (0.07) | 2.6 (0.16) |
| FVC (% predicted) | 73 (2.79) | 74 (1.75) | 79 (3.67) |
| FEV1/FVC (observed) | 32 (1.23) | 33 (0.67) | 32 (1.20) |
| FEV1/FVC (% predicted) | 45 (1.65) | 47 (0.93) | 45 (1.71) |
| FRC (observed) | 6.4 (0.21) | 5.8 (0.13) | 5.9 (0.31) |
| FRC (% predicted) | 195 (4.64) | 183 (3.80) | 184 (8.27) |
| RV (observed) | 5.3 (0.19) | 4.9 (0.12) | 5.0 (0.27) |
| RV (% predicted) | 240 (7.89) | 236 (5.68) | 236 (12.1) |
| TLC (observed) | 8.1 (0.24) | 7.9 (0.14) | 8.0 (0.34) |
| TLC (% predicted) | 146 (2.64) | 142 (1.73) | 147 (4.13) |
| TLCHe (observed) | 4.1 (0.17) | 4.3 (0.10) | 4.6 (0.23) |
| TLCHe (% predicted) | 73 (2.18) | 77 (1.31) | 84 (3.28) |
| Trapped gas | 4.0 (0.19) | 3.6 (0.12) | 3.3 (0.32) |
| Tlco (observed) | 7.2 (0.34) | 9.4 (0.63) | 8.8 (0.65) |
| Tlco (% predicted) | 35 (1.63) | 42 (2.43) | 38 (2.51) |
| MIPRV (–cm H2O)* | −54 (4.50) | −47.2 (2.94) | −48.3 (5.44) |
| MEPTLC (cm H2O)* | 87.9 (5.16) | 86.5 (4.90) | 76.5 (6.54) |
| Pao2 (kPa) | 9.3 (0.2) | 8.9 (0.1) | 9.2 (0.4) |
| Paco2 (kPa) | 5.9 (0.1) | 6.0 (0.1) | 5.6 (0.2) |
| Sao2 (%) | 93.3 (0.36) | 91.3 (0.43) | 89.1 (3.21) |