Mean peak plasma concentration (Cmax) and area under the plasma concentration time curve (AUC) for fluticasone propionate and budesonide in healthy subjects and subjects with moderately severe asthma
| Fluticasone propionate | Budesonide | |||||
|---|---|---|---|---|---|---|
| Healthy subjects | Asthmatic subjects | Difference (95% CI), p value | Healthy subjects | Asthmatic subjects | Difference (95% CI), p value | |
| Cmax (pg/ml) | 130 | 78 | 52 (–11 to 115), p=0.1 | 2432 | 2276 | 157 (–1026 to 1339), p=0.8 |
| AUC (pg/ml/h) | 712 | 404 | 307 (62 to 552), p=0.02 | 6467 | 7293 | –826 (–3143 to 1493), p=0.5 |