Temperature dependency of liposome uptake by type II pneumocytes isolated from lungs exposed to 10 ppm NO2 under different conditions
| −SP-A | +SP-A | ||||
|---|---|---|---|---|---|
| 4°C | 37°C | 4°C | 37°C | ||
| Values are mean (SE) pmol cholesterol oleate/mg protein; n=3–4 experiments. | |||||
| **p<0.01. 4°C v 37°C in the presence of SP-A. | |||||
| Control | 146.3 (9.8) | 168.5 (13.9) | 192.1 (3.3) | 477.8 (12.9)** | |
| 3 days | 190.0 (6.5) | 240.0 (11.0) | 202.9 (5.6) | 542.4 (5.7)** | |
| 20 days | 180.0 (7.7) | 204.4 (9.9) | 176.9 (10.2) | 547.7 (12.6)** | |
| 28 days | 246.0 (11.4) | 314.4 (13.6) | 263.8 (7.9) | 800.3 (10.7)** | |