Significance of correlations between serological parameters and conventional measures of disease severity within individual patients during the entire treatment period
| Anti-GM-CSF Ab (μg/ml) | SP-A (μg/ml) | SP-B (μg/ml) | LDH (%ULN) | |||||
|---|---|---|---|---|---|---|---|---|
| No | p value | No | p value | No | p value | No | p value | |
| [A–a]Do2=alveolar-arterial oxygen gradient; VC=vital capacity; Tlco=carbon monoxide transfer factor. | ||||||||
| p values are calculated from the signed rank test for association within patients (see Appendix). | ||||||||
| [A – a]Do2 (mm Hg) | 98 | NS | 102 | 0.054 | 102 | NS | 132 | 0.010 |
| Tlco (% predicted) | 69 | NS | 74 | NS | 74 | NS | 100 | NS |
| VC (% predicted) | 78 | NS | 80 | NS | 80 | NS | 106 | 0.019 |