Parameter | Anti-GM-CSF Ab (μg/ml) | p value | SP-A (μg/ml)* | p value | SP-B (μg/ml)† | p value | LDH (%ULN) | p value |
---|---|---|---|---|---|---|---|---|
Po2=arterial oxygen tension; [A–a]Do2=alveolar-arterial oxygen gradient; VC=vital capacity; Tlco=carbon monoxide transfer factor. | ||||||||
*Normal range for serum level of SP-A is <0.25 μg/ml. Values were not normally distributed so analysis was performed following log10 transformation of data. | ||||||||
†Normal range for serum level of SP-B is <2.6 μg/ml. Values were not normally distributed so analysis was performed following log10 transformation of data. | ||||||||
Arterial Po2 (mm Hg) (n=11) | –0.123 | NS | –0.704 | 0.01 | –0.247 | NS | –0.175 | NS |
[A – a]Do2 (mm Hg) (n=11) | 0.123 | NS | 0.715 | 0.009 | 0.088 | NS | 0.025 | NS |
VC (% predicted) (n=12) | –0.022 | NS | –0.646 | 0.02 | 0.210 | NS | –0.461 | NS |
Tlco (% predicted) (n=12) | 0.017 | NS | –0.829 | 0.0009 | 0.179 | NS | –0.482 | NS |
LDH (%ULN) (n=12) | 0.237 | NS | 0.462 | 0.1 | 0.056 | NS | ||
SP-B (μg/ml) (n=12)† | 0.123 | NS | –0.321 | NS | ||||
SP-A (μg/ml) (n=12)* | 0.189 | NS |