Mucus | Damaged mucus | Ciliated mucosa | Unciliated mucosa | |||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
15 m | 3 h | 24 h | 7 d | 14 d | 15 m | 3 h | 24 h | 7 d | 14 d | 15 m | 3 h | 24 h | 7 d | 14 d | 15 m | 3 h | 24 h | 7 d | 14 d | |
Figures are the percentage of the mucosal surface surveyed occupied by a particular feature. n=number of experiments in which the mucosal feature was observed out of six. | ||||||||||||||||||||
15 m=15 minutes; 3 h and 24 h=3 and 24 hours; 7d and 14d = 7 and 14 days incubation time. | ||||||||||||||||||||
MAC | ||||||||||||||||||||
Mean | 22.7 | 19.7 | 15.1 | 18.3 | 10.8 | 24.0 | 18.6 | 20.5 | 15.3 | 37.4 | 14.2 | 16.9 | 12.4 | 19.6 | 12.2 | 39.1 | 44.8 | 52.0 | 46.9 | 39.6 |
SE | 9.2 | 6.4 | 7.1 | 2.4 | 5.5 | 12.6 | 10.3 | 11.0 | 6.2 | 16.9 | 7.8 | 7.5 | 7.5 | 9.3 | 4.3 | 11.9 | 10.2 | 12.8 | 6.8 | 10.3 |
Median | 15.5 | 16.2 | 13.2 | 19.1 | 6.1 | 14.8 | 12.5 | 12.7 | 14.8 | 17.6 | 8.9 | 10.4 | 9.6 | 13.4 | 14.0 | 40.8 | 45.7 | 42.2 | 42.4 | 43.7 |
n | 5/6 | 5/6 | 5/6 | 6/6 | 4/6 | 5/6 | 5/6 | 5/6 | 4/6 | 5/6 | 6/6 | 6/6 | 6/6 | 5/6 | 6/6 | 6/6 | 6/6 | 6/6 | 6/6 | 6/6 |
TB | ||||||||||||||||||||
Mean | 12.8 | 18.5 | 17.4 | 13.5 | 16.6 | 19.3 | 28.7 | 21.2 | 25.3 | 29.0 | 20.3 | 21.6 | 15.8 | 11.8 | 16.3 | 47.6 | 31.2 | 45.6 | 49.4 | 38.1 |
SE | 5.1 | 6.5 | 3.7 | 4.7 | 5.7 | 8.8 | 13.1 | 11.4 | 11.2 | 19.4 | 18.6 | 16.2 | 14.3 | 8.5 | 8.0 | 7.0 | 7.8 | 11.3 | 6.8 | 9.0 |
Median | 11.6 | 16.4 | 13.6 | 14.5 | 11.3 | 14.7 | 16.9 | 14.1 | 17.8 | 19.3 | 11.3 | 12.8 | 6.4 | 0 | 11.1 | 46.7 | 28.5 | 33.9 | 44.1 | 35.1 |
n | 5/6 | 4/6 | 4/6 | 4/6 | 5/6 | 5/6 | 4/6 | 4/6 | 4/6 | 5/6 | 6/6 | 5/6 | 5/6 | 6/6 | 6/6 | 6/6 | 6/6 | 6/6 | 6/6 | 6/6 |
SM | ||||||||||||||||||||
Mean | 16.8 | 26.4 | 19.0 | 15.1 | 11.0 | 24.7 | 25.9 | 22.8 | 26.5 | 31.3 | 15.3 | 19.3 | 17.9 | 16.8 | 16.3 | 43.2 | 28.4 | 40.3 | 41.6 | 41.4 |
SE | 2.4 | 18.4 | 8.1 | 3.2 | 2.7 | 10.5 | 9.3 | 16.2 | 11.0 | 25.8 | 7.4 | 8.6 | 8.6 | 8.3 | 6.8 | 6.2 | 4.7 | 5.7 | 7.5 | 6.5 |
Median | 17.1 | 14.6 | 15.5 | 16.5 | 11.3 | 19.4 | 22.6 | 12.9 | 15.6 | 19.4 | 12.5 | 16.7 | 9.3 | 11.8 | 17.1 | 44.8 | 30.7 | 42.4 | 42.1 | 38.0 |
n | 5/6 | 5/6 | 5/6 | 5/6 | 5/6 | 5/6 | 5/6 | 5/6 | 5/6 | 6/6 | 6/6 | 6/6 | 5/6 | 6/6 | 5/6 | 6/6 | 6/6 | 6/6 | 6/6 | 6/6 |