Clinical characteristics of study subjects
| Normal controls | COPD patients | |
|---|---|---|
| Values are mean (SD). | ||
| FEV1=forced expiratory volume in 1 second; FVC = forced vital capacity; Tlco=carbon monoxide transfer factor; ND=not determined. | ||
| *p<0.001 compared with normal controls. | ||
| Subject number (M/F) | 15 (12/3) | 30 (25/5) |
| Age (years) | 58.5 (5.5) | 62.4 (4.5) |
| FEV1 (% predicted) | 99.5 (4.5) | 52.1 (13.8)* |
| FEV1/FVC (%) | 90.4 (2.5) | 44.2 (8.3)* |
| Tlco (%) | ND | 43.3 (9.4) |
| Sputum | ||
| % neutrophils | 22.3 (3.9) | 57.2 (10.9)* |
| IL-8 (ng/ml) | 0.88 (0.35) | 8.08 (3.80)* |