Exacerbators | Non-exacerbators | Mean (95% CI) difference | p value | |
---|---|---|---|---|
Total | ||||
4 weeks | 46.9 (19.2) | 42.5 (19.3) | 4.4 (1.3 to 7.6) | 0.006 |
12 weeks | 45.9 (20.0) | 37.8 (21.9) | 8.1 (4.4 to 11.8) | <0.0001 |
26 weeks | 45.6 (21.3) | 36.0 (21.1) | 9.6 (5.7 to 13.4) | <0.0001 |
Symptoms | ||||
4 weeks | 66.6 (20.3) | 57.9 (22.1) | 8.7 (4.4 to 13.1) | 0.0001 |
12 weeks | 56.8 (24.8) | 41.7 (25.8) | 16.3 (10.9 to 21.8) | <0.0001 |
26 weeks | 59.5 (26.7) | 43.2 (25.5) | 16.2 (10.6 to 21.9) | <0.0001 |
Activity | ||||
4 weeks | 54.8 (26.2) | 51.2 (25.9) | 3.6 (–0.1 to 7.3) | 0.06 |
12 weeks | 54.5 (25.4) | 49.2 (27.9) | 5.4 (1.0 to 9.7) | 0.02 |
26 weeks | 56.3 (26.7) | 46.9 (28.4) | 9.4 (4.7 to 14.1) | 0.0001 |
Impacts | ||||
4 weeks | 36.2 (19.6) | 32.1 (20.1) | 4.1 (0.7 to 7.4) | 0.02 |
12 weeks | 36.3 (20.3) | 28.6 (21.2) | 7.7 (3.9 to 11.4) | 0.0001 |
26 weeks | 35.5 (22.7) | 26.9 (21.5) | 8.5 (4.5 to 12.6) | 0.0001 |