Table 2

Recommended criteria for definition of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Modified from Bernard et al42

TimingOxygenationChest radiographPulmonary artery wedge pressure
ALIAcute onsetPao2/Fio2 ⩽40 kPa (regardless of PEEP level)Bilateral infiltrates on frontal chest radiograph⩽18 mm Hg or no clinical evidence of left atrial hypertension
ARDSAcute onsetPao2/Fio2 ⩽26.7 kPa (regardless of PEEP level)Bilateral infiltrates on frontal chest radiograph⩽18 mm Hg or no clinical evidence of left atrial hypertension