Baseline characteristics for patients with a histological diagnosis of UIP or NSIP
| Histological UIP | |||||
|---|---|---|---|---|---|
| HRCT UIP (1) | HRCT not UIP (2) | Histological NSIP (3) | p value (1)=(2)=(3) | p value (1)=(2) | |
| Values are mean (SD). | |||||
| UIP=usual interstitial pneumonia; NSIP=non-specific interstitial pneumonia; onset=duration of symptoms before surgical lung biopsy; FVC=forced vital capacity; FEV1=forced expiratory volume in 1 second; TLC=total lung capacity; Tlco=carbon monoxide transfer factor. | |||||
| *Additional comparisons with NSIP that were significant at the p<0.05 level in post hoc analysis were: age (1) v (3), (2) v (3); (1) and (2) v (3); Tlco (% pred) (1) v (3). | |||||
| Sex (F/M) | 8/19 | 26/20 | 13/10 | 0.060 | 0.03 |
| Age (years) | 64 (8) | 60 (12) | 54 (11) | 0.004* | 0.06 |
| Onset (years) | 3.6 (2.6) | 2.2 (2.6) | 2.5 (3.7) | 0.12 | 0.03 |
| Weight (kg) | 84 (16) | 86 (19) | 88 (18) | 0.70 | 0.67 |
| Non-smokers (%) | 19.2 (39.4) | 46.5 (49.9) | 39.1 (48.8) | 0.07 | 0.03 |
| Pack years | 18 (17) | 19 (26) | 24 (28) | 0.69 | 0.86 |
| FVC (l) | 2.95 (1.0) | 2.36 (0.8) | 2.6 (0.8) | 0.18 | 0.11 |
| FVC (% pred) | 76 (21) | 64 (19) | 70 (17) | 0.18 | 0.12 |
| FEV1 (l) | 2.32 (0.8) | 1.93 (0.7) | 1.98 (0.6) | 0.29 | 0.18 |
| FEV1 (% pred) | 85 (23) | 72 (21) | 72 (17) | 0.21 | 0.15 |
| TLC (l) | 4.56 (1.1) | 4.05 (1.4) | 4.57 (1.9) | 0.33 | 0.25 |
| TLC (% pred) | 79 (15) | 73 (19) | 84 (18) | 0.17 | 0.33 |
| Tlco | 10.31 (5.7) | 14.47 (5.5) | 13.61 (3.11) | 0.08 | 0.07 |
| Tlco (% pred) | 40 (20) | 56 (16) | 57 (14) | 0.03* | 0.05 |