Differential cell counts (cytospins) and lymphocyte profiles (flow cytometry) in induced sputum
| Healthy controls (n=6) | Asthma (n=8) | COPD (n=7) | |
|---|---|---|---|
| Results are expressed as mean (SE). | |||
| Cytospins | |||
| Total cells (106) | 27.19 (20.90) | 13.75 (2.60) | 52.78 (17.78) |
| Macrophages (%) | 55.17 (9.80) | 30.87 (12.74) | 25.41 (4.52) |
| Neutrophils (%) | 44.10 (9.88) | 67.40 (11.98) | 70.86 (3.84) |
| Eosinophils (%) | 0.43 (0.21) | 1.37 (0.42) | 3.59 (1.59) |
| Lymphocytes (%) | 0.30 (0.10) | 0.36 (0.21) | 0.15 (0.10) |
| Flow cytometry | |||
| CD4 lymphocytes (%) | 2.01 (1.32) | 1.55 (0.75) | 0.97 (0.30) |
| CD8 lymphocytes (%) | 0.42 (0.15) | 0.28 (0.11) | 0.38 (0.14) |
| CD4:CD8 ratio | 4.90 (1.58) | 5.49 (1.16) | 2.79 (0.96) |