Characteristics of participants
| Age (years) | Atopic status* | FENO (ppb)† | FEV1 (% predicted)‡ | PC20FEV1 histamine (mg/ml) | |
|---|---|---|---|---|---|
| SD=standard deviation; FENO=fractional exhaled concentration of nitric oxide; FEV1=forced expiratory volume in 1 s; PC20FEV1 histamine=provocative concentrations of histamine causing a 20% fall in FEV1 in the screening period. | |||||
| *Atopic status as determined by the number of wheal responses to 10 common allergen extracts (Vivodiagnost, ALK, Benelux). | |||||
| †Values obtained at the first randomised visit. | |||||
| ‡Baseline values as percentage of predicted values in the screening period. Patients have also been described elsewhere.16 | |||||
| Mean | 22.1 | 4.2 | 33.5 | 94.4 | 1.56 |
| SD | 2.6 | 0.9 | 23.7 | 7.2 | |
| Range | 19–26 | 3–6 | 14–95 | 81–104 | 0.29–4.23 |