Bronchoscopy subject profiles
| Asthmatics (n=92) | Normal controls (n=26) | |||
|---|---|---|---|---|
| BAL cells | Biopsies | BAL cells | Biopsies | |
| *Dose in μg per day of beclomethasone dipropionate. | ||||
| †Matching BAL cell and biopsy samples were obtained from 53 patients. | ||||
| ‡Matching BAL cell and biopsy samples were obtained from 14 normal controls. | ||||
| n | 75† | 70 | 23‡ | 17 |
| Sex (M:F) | 46:29 | 40:30 | 15:8 | 9:8 |
| Median (range) age | 37 (21–69) | 38 (21–69) | 33 (20–61) | 33 (20–61) |
| Atopy (+/–) | 63/12 | 58/12 | 12/11 | 8/9 |
| ICS use (+/–) | 62/13 | 58/12 | 0/23 | 0/17 |
| Median (range) ICS dose/day (BDP)* | 400 (100–900) | 400 (100–900) | – | – |
| Median (range) PD20 methacholine (mg) | 0.027 (0.001–6.4) | 0.026 (0.001–6.4) | >3.4 | >3.4 |
| Median (range) FEV1 (% predicted) | 90 (65–128) | 88 (68–120) | 111 (91–132) | 107 (91–132) |