Characteristics of respondents reporting asthmatic reactions to aspirin in the Asthma Foundation cohort
| Aspirin intolerant asthma | |||||
|---|---|---|---|---|---|
| Characteristic | No | Yes* | OR | 95% CI† | p Value‡ |
| *Based on reported asthmatic responses to aspirin and/or NSAIDs on at least two occasions. †Confidence intervals calculated using the approximation of Woolfe. ‡Two tailed significance level based on Fisher's exact test. §Missing data reflect individuals who did not complete question (or questions) relating to parameter. | |||||
| Age (years) | |||||
| 18–35 | 76 | 12 | 1.00 | ||
| >35 | 252 | 26 | 0.65 | 0.31 to 1.36 | 0.315 |
| Sex | |||||
| Male | 93 | 7 | 1.00 | ||
| Female | 235 | 31 | 1.75 | 0.75 to 4.12 | 0.249 |
| Asthma severity scale§ | |||||
| Mild to moderate | 246 | 22 | 1.00 | ||
| Severe to very severe | 70 | 15 | 2.40 | 1.18 to 4.86 | 0.023 |
| Asthma attacks | |||||
| 0–1 | 219 | 17 | 1.00 | ||
| ≥2 | 109 | 21 | 2.48 | 1.26 to 4.90 | 0.011 |
| Doctor visits§ | |||||
| 0–1 | 135 | 9 | 1.00 | ||
| ≥2 | 185 | 28 | 2.27 | 1.04 to 4.97 | 0.050 |
| Self-classification severity§ | |||||
| Mild to moderate | 267 | 26 | 1.00 | ||
| Severe to very severe | 55 | 12 | 2.24 | 1.07 to 4.71 | 0.045 |
| Alternative health consultation | 35 | 5 | 1.32 | 0.48 to 3.61 | 0.578 |
| Taking oral corticosteroids | 43 | 8 | 1.77 | 0.76 to 4.11 | 0.213 |
| Atopic | 112 | 23 | 2.96 | 1.48 to 5.89 | 0.002 |
| Hayfever | 256 | 34 | 2.39 | 0.82 to 6.96 | 0.138 |
| Nasal polyps | 46 | 13 | 3.19 | 1.52 to 6.68 | 0.004 |
| Exercise/cold air asthma | 251 | 32 | 1.64 | 0.66 to 4.06 | 0.412 |
| Seasonal asthma | 203 | 27 | 1.51 | 0.72 to 3.16 | 0.293 |
| Wine induced asthma | 90 | 21 | 3.27 | 1.65 to 6.47 | 0.001 |
| Sulphite induced asthma | 38 | 13 | 3.97 | 1.87 to 8.41 | 0.001 |