Table 1

Patient and sputum characteristics

PiZ (n=11)PiM (n=11)
FEV1= forced expiratory volume in one second; VC=vital capacity; M=mucoid; MP=mucopurulent; cfu=colony forming units.
Data for age, FEV1 (% predicted) and FEV1/VC (%) are mean (SD).
*p<0.05.
Age47 (8)64 (6)*
M/F8:36:5
Current (ex) smokers3 (8)5 (6)
Inhaled corticosteroids77
Stable state FEV1 (% predicted)28.3 (19.5)33.7 (14.4)
Stable state FEV1/VC (%)30.7 (10.1)40.1 (17.0)
Macroscopic sputum appearance (M/MP)2/92/9
Sputum bacterial load >107 (cfu/ml)44