Mean (SD) values of indices before histamine challenge, log dose slopes at sea level and mean change at 5000 m with 95% confidence interval (CI) for the difference
| Sea level | Altitude minus sea level | ||
|---|---|---|---|
| Mean (SD) | Mean | 95% CI | |
| For definition of abbreviations see footnote to table 2. The suffix P denotes that this index is taken from the partial loop. | |||
| ***p<0.0005; **p<0.005; *p<0.05 (paired t test with Bonferroni correction for multiple comparisons). | |||
| FVC | 4.95 (0.98) | –0.18* | –0.27 to 0.08 |
| FEV1 | 3.87 (0.77) | 0.02 | –0.10 to 0.13 |
| PEF | 8.85 (2.08) | 1.71*** | 1.28 to 2.13 |
| FEV1 % | 78.37 (5.45) | 2.98** | 1.52 to 4.43 |
| α175% | 0.31 (0.05) | –0.05*** | –0.06 to –0.04 |
| MEF30% | 2.18 (0.77) | 0.07 | –0.12 to 0.26 |
| α175%P | 0.33 (0.08) | –0.03 | –0.07 to 0.01 |
| MEF30%P | 2.45 (0.70) | –0.52 | –0.92 to –0.12 |
| MP30% | 0.87 (0.20) | 0.28** | 0.14 to 0.42 |
| LDSFEV1 | 0.68 (0.44) | 0.00 | –0.32 to 0.33 |
| LDSα175% | 0.80 (0.45) | –0.04 | –0.49 to 0.40 |
| LDSMEF30% | 0.89 (0.39) | –0.06 | –0.37 to 0.26 |
| LDSα175% P | 1.19 (0.38) | 0.01 | –0.40 to 0.42 |
| LDSMEF30%P | 1.31 (0.32) | –0.09 | –0.49 to 0.30 |