Characteristics of study subjects
|
Healthy controls (n=23) |
Stable COPD (n=55) |
Exacerbations of COPD1-150
(n=13) | |
| Age (years) | 64 (60–72)1-151 | 69 (41–78)1-152 | 68 (54–82) |
| M:F | 16:7 | 55:0 | 9:4 |
| FVC (% predicted) | 119 (98–150) | 85 (47–122)1-153 | 71 (26–111) |
| FEV1 (% predicted) | 110 (77–147) | 34 (15–78)1-153 | 34 (19–51) |
| FEV1/FVC (%) | 73 (62–83) | 31 (15–68)1-153 | 40 (21–67)1-154 |
| Pao 2 (kPa) | 11.4 (9.2–14.6) | 9.4 (7.5–13.0)1-153 | 8.6 (6.3–10.2)1-154 |
| Paco 2 (kPa) | 5.5 (4.6–6.2) | 5.7 (4.1–7.6) | 6.2 (4.5–7.2)1-154 |
| pH | 7.41 (7.38–7.43) | 7.41 (7.30–7.50) | 7.42 (7.34–7.49) |
FVC = forced vital capacity; FEV1 = forced expiratory volume in one second; Pao 2, Paco 2 = arterial oxygen and carbon dioxide tension.
↵1-150 Patient characteristics at day 1 after admission to hospital for exacerbation of disease.
↵1-151 Values are median (range), or absolute numbers for sex.
↵1-152 p<0.05 v healthy controls;
↵1-153 p<0.005v healthy controls;
↵1-154 p<0.05v patients with stable COPD.