Table 1

Mean (SE) baseline demographic data for the 20 subjects with COPD studied

All (n=20) NEP=0 (n=9) NEP=1 (n=4) NEP=2 (n=7)
Age (years)69.9  (1.5)61.4  (7.4)67.0  (2.0)73.9  (1.9)
M:F15:57:24:04:3
BMI (kg/m2)24.7 (2.5)25.5 (1.1)21.6 (1.1)25.4 (1.8)
FEV1 (l)0.78 (0.05)0.96 (0.06)0.61 (0.1)1-150 0.65 (0.06)1-150
FEV1 (% predicted)29.6 (2.3)34.2 (2.4)20.5 (2.51-150)28.9 (4.8)
FVC (l)2.26 (0.13)2.62 (0.19)1.98 (0.18)1.95 (0.19)1-150
FVC (% predicted)64.6 (3.2)71.4 (4.0)51.3 (4.1)1-150 63.4 (5.7)
FEV1/FVC (%)35.5 (2.2)37.6 (2.8)30.8 (3.3)35.4 (5.1)
IC (l)1.65 (0.09)1.9 (0.2)1.5 (0.1)1.4 (0.1)1-150
SVC (l)2.65 (0.16)3.0 (0.2)2.5 (0.1)2.3 (0.3)1-150
TLC (l)7.48 (0.34)7.5 (0.5)8.5 (0.9)6.9 (0.6)
Pao 2 (kPa)8.75 (0.26)9.3 (0.4)8.3 (0.3)8.3 (0.4)
Paco 2(kPa)5.52 (0.17)5.3 (0.2)5.6 (0.4)5.8 (0.3)
SGRQ (%)62.7 (3.3)62.7 (5.2)64.7 (7.9)61.6 (5.9)
  • BMI = body mass index; FEV1 = forced expiratory volume in one second; FVC = forced vital capacity; IC = inspiratory capacity; SVC = slow vital capacity; RLC = total lung capacity; Pao 2, Paco 2 = arterial oxygen and carbon dioxide tensions; SGRQ = St George's Respiratory Questionnaire; NEP = negative expiratory pressure; 0 = no flow limitation; 1 = partial flow limitation; 2 = complete flow limitation.

  • 1-150 p<0.05.