Wheeze in the past year without a diagnosis of asthma | Wheeze in the past year and diagnosis of asthma | ||||||
---|---|---|---|---|---|---|---|
N | Adjusted* OR | 95% CI | p value** | Adjusted* OR | 95% CI | p value** | |
*Adjustment for all variables listed. | |||||||
**Significance levels are based on a test for heterogeneity except for age and social class which are based on tests for trend using ordered categories. | |||||||
***I=professional; II=managerial; IIInm=clerical; IIIm=skilled manual; IV=semi-skilled manual; V=unskilled manual. | |||||||
Sex | |||||||
Female | 7010 | 1 | (reference) | 0.971 | 1 | (reference) | <0.001 |
Male | 5082 | 1.00 | 0.86 to 1.16 | 0.71 | 0.61 to 0.83 | ||
Age | |||||||
11–19 | 1838 | 1 | (reference) | <0.001 | 1 | (reference) | 0.009 |
20–29 | 1703 | 0.88 | 0.64 to 1.21 | 0.95 | 0.75 to 1.20 | ||
30–39 | 2451 | 1.19 | 0.91 to 1.57 | 0.62 | 0.49 to 0.79 | ||
40–49 | 1931 | 1.54 | 1.17 to 2.04 | 0.75 | 0.58 to 0.97 | ||
50–59 | 1432 | 1.81 | 1.35 to2.42 | 0.61 | 0.44 to 0.83 | ||
60–69 | 1356 | 1.80 | 1.34 to 2.42 | 0.77 | 0.57 to 1.04 | ||
70–79 | 904 | 2.10 | 1.52 to 2.89 | 0.89 | 0.63 to 1.25 | ||
80–89 | 430 | 2.93 | 2.03 to 4.25 | 0.66 | 0.39 to 1.12 | ||
90+ | 47 | 2.51 | 0.95 to 6.60 | 0.02 | 0.00 to 32.52 | ||
Social class*** | |||||||
I | 1031 | 1 | (reference) | 0.009 | 1 | (reference) | 0.618 |
II | 3900 | 1.15 | 0.86 to 1.54 | 0.80 | 0.61 to 1.04 | ||
IIInm | 1632 | 1.15 | 0.83 to 1.60 | 0.84 | 0.61 to 1.14 | ||
IIIm | 3054 | 1.44 | 1.07 to 1.94 | 0.89 | 0.68 to 1.17 | ||
IV | 1382 | 1.31 | 0.94 to 1.84 | 0.90 | 0.65 to 1.23 | ||
V | 489 | 1.41 | 0.93 to 2.14 | 0.80 | 0.51 to 1.24 | ||
Urban/rural | |||||||
Rural | 2992 | 1 | (reference) | 0.099 | 1 | (reference) | 0.933 |
Urban | 9100 | 1.16 | 0.97 to 1.37 | 0.99 | 0.83 to 1.18 | ||
Log total IgE | |||||||
0–3 | 1312 | 1 | (reference) | 0.013 | 1 | (reference) | <0.001 |
4–9 | 1547 | 1.01 | 0.74 to 1.39 | 1.46 | 0.88 to 2.40 | ||
10–31 | 2970 | 1.08 | 0.87 to 1.44 | 1.64 | 1.04 to 2.58 | ||
32–99 | 3024 | 1.07 | 0.81 to 1.42 | 2.72 | 1.76 to 4.21 | ||
100–315 | 2132 | 1.35 | 1.00 to 1.82 | 3.69 | 2.37 to 5.74 | ||
316–999 | 847 | 1.55 | 1.08 to 2.24 | 4.49 | 2.80 to 7.18 | ||
1000+ | 260 | 1.08 | 0.58 to 1.99 | 7.01 | 4.15 to 11.85 | ||
HDM IgE | |||||||
0–0.3 | 9587 | 1 | (reference) | <0.001 | 1 | (reference) | <0.001 |
0.4–10.0 | 1436 | 1.26 | 1.00 to 1.59 | 2.01 | 1.62 to 2.48 | ||
>10 | 1069 | 2.07 | 1.56 to 2.74 | 4.92 | 3.96 to 6.11 |