Baseline data by treatment and sequence
| Baseline by treatment | Baseline by sequence | |||
|---|---|---|---|---|
| BEC-HFA | FLU-HFA | 1st | 2nd | |
| BEC-HFA=HFA-134a solution formulation of beclomethasone dipropionate; FLU-HFA=HFA-134a suspension formulation of fluticasone propionate; PD20=dose of methacholine provoking a fall in FEV1 of 20% or more; NO=nitric oxide; FEV1=forced expiratory volume in 1 second; PEF=peak expiratory flow; OUCC=overnight urinary cortisol/creatinine. | ||||
| Values are means (SE) except methacholine PD20, NO, and OUCC which are expressed as geometric means (SE). | ||||
| *Denotes significant (p<0.05) difference between baseline values. | ||||
| Methacholine PD20 (μg) | 97.0 (20.8) | 96.2 (25.4) | 80.8 (16.8)* | 115.4 (30.4) |
| Exhaled NO (ppb) | 11.3 (1.9)* | 8.3 (1.3) | 10.9 (2.0) | 8.6 (1.2) |
| FEV1 (% predicted) | 87.9 (2.4) | 89.1 (2.9) | 87.9 (2.6) | 89.1 (2.7) |
| Morning PEF (l/min) | 437 (19) | 445 (21) | 440 (19) | 442 (20) |
| OUCC (nmol/mmol) | 7.08 (0.99) | 6.14 (0.91) | 6.91 (0.84) | 6.07 (1.11) |