Median (range) percentage of total lymphocytes, CD4+, CD8+, γδ T cells, and Vδ1 and Vδ2 subsets among TB patients and controls
| Cell population | TB HIV+ (n=20) | HIV+ asymptomatic (n=9) | p value* | TB HIV– (n=54) | Blood donors (n=39) | p value† |
|---|---|---|---|---|---|---|
| *Mann-Whitney U test comparing HIV+TB patients and HIV+ asymptomatic patients; †Mann-Whitney U test comparing HIV– TB patients and blood donors; ‡n=23 for total lymphocytes, CD4+ and CD8+ cell counts. | ||||||
| Total lymphocytes | 22.0 (4.6–77.0) | 20.4 (6.8–68.0) | 0.85 | 23.8 (5.4–65.0) | 34.5 (24.8–47.9)‡ | <0.0005 |
| CD4+ | 15.0 (1.2–38.0) | 12.6 (2.6–38.7) | 0.73 | 43.1 (3.4–57.3) | 46.1 (36.9–60.9) | 0.05 |
| CD8+ | 56.6 (33.7–72.3) | 62.1 (4.1–78.8) | 0.5 | 24.5 (6.1–68.2) | 24.5 (14.5–37.7) | 0.92 |
| Total γδ T cells | 4.2 (2.0–12.3) | 3.7 (1.8–9.8) | 0.32 | 3.35 (0.7–11.9) | 4.0 (0.8–15.3) | 0.16 |
| Vδ1 | 1.75 (0.9–11.3) | 1.8 (0.9–6.3) | 0.83 | 1.0 (0.1–6.3) | 0.9 (0.1–6.8) | 0.75 |
| Vδ2 | 1.05 (0.3–3.9) | 0.9 (0.3–3.7) | 0.34 | 1.5 (0.2–11.8) | 2.1 (0.5–13.4) | 0.05 |